The below PTCB Practice Test 3 covers the Patient Safety and Quality Assurance section, which accounts for 26.25% of the PTCB Exam. This is one of the most important domains, as it focuses on preventing medication errors, ensuring proper medication storage, and following quality control procedures. Practicing these questions will help you build confidence in identifying potential safety risks, handling high-alert medications, and understanding error reporting systems.
PTCB Practice Test 3 – 50 Practice Questions
Use this test to strengthen your knowledge and sharpen your skills in maintaining patient safety — a key responsibility for every pharmacy technician. Review the explanations carefully to deepen your understanding and get one step closer to passing your PTCB exam with confidence!
PTCB Practice Test 3
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PTCB Practice Test 3
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Question 1 of 50
1. Question
A technician notices that a laminar flow hood has not been cleaned in several hours. What should be done?
Correct
A laminar flow hood must be cleaned regularly to maintain sterility. Failing to do so can compromise compounded medications and patient safety.
Incorrect
A laminar flow hood must be cleaned regularly to maintain sterility. Failing to do so can compromise compounded medications and patient safety.
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Question 2 of 50
2. Question
A pharmacist notices that a technician incorrectly stored a refrigerated vaccine at room temperature for 12 hours. What should be done?
Correct
Temperature deviations affect vaccine potency. The manufacturer must confirm if the vaccine is still usable.
Incorrect
Temperature deviations affect vaccine potency. The manufacturer must confirm if the vaccine is still usable.
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Question 3 of 50
3. Question
Which of the following must be reported as a medication error?
Correct
Incorrect dosage instructions on a prescription can lead to serious harm and must be reported as a medication error.
Incorrect
Incorrect dosage instructions on a prescription can lead to serious harm and must be reported as a medication error.
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Question 4 of 50
4. Question
Which organization maintains a list of high-alert medications?
Correct
ISMP maintains a list of high-alert medications, which have a high risk of causing harm if used incorrectly, helping pharmacies implement safety measures.
Incorrect
ISMP maintains a list of high-alert medications, which have a high risk of causing harm if used incorrectly, helping pharmacies implement safety measures.
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Question 5 of 50
5. Question
A patient reports that their warfarin tablets look different than usual. What should the pharmacy technician do next?
Correct
Medication appearance changes should always be investigated to rule out dispensing errors or manufacturer changes. The pharmacist should verify the correct medication before the patient takes it.
Incorrect
Medication appearance changes should always be investigated to rule out dispensing errors or manufacturer changes. The pharmacist should verify the correct medication before the patient takes it.
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Question 6 of 50
6. Question
What should be done when cleaning a laminar airflow hood in a sterile compounding area?
Correct
Laminar airflow hoods must be cleaned with isopropyl alcohol in a back-to-front motion to maintain sterility and prevent contamination.
Incorrect
Laminar airflow hoods must be cleaned with isopropyl alcohol in a back-to-front motion to maintain sterility and prevent contamination.
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Question 7 of 50
7. Question
What should be done if a medication error is discovered before the patient receives the drug?
Correct
Medication errors must be corrected and documented, even if the patient has not received the drug, to ensure accountability and prevent future mistakes.
Incorrect
Medication errors must be corrected and documented, even if the patient has not received the drug, to ensure accountability and prevent future mistakes.
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Question 8 of 50
8. Question
A nurse calls the pharmacy reporting that a patient developed a severe rash after taking their first dose of allopurinol. What should the pharmacy do?
Correct
Allopurinol hypersensitivity can be life-threatening. Immediate prescriber notification and documentation are essential to prevent severe allergic reactions.
Incorrect
Allopurinol hypersensitivity can be life-threatening. Immediate prescriber notification and documentation are essential to prevent severe allergic reactions.
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Question 9 of 50
9. Question
Why is it important for pharmacy technicians to follow hygiene standards when handling medications?
Correct
Proper hygiene practices prevent contamination of medications, ensuring product safety and patient health.
Incorrect
Proper hygiene practices prevent contamination of medications, ensuring product safety and patient health.
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Question 10 of 50
10. Question
Which method is recommended for cleaning pharmacy counting trays?
Correct
Using an alcohol-based disinfectant prevents cross-contamination between medications and ensures hygiene in medication dispensing.
Incorrect
Using an alcohol-based disinfectant prevents cross-contamination between medications and ensures hygiene in medication dispensing.
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Question 11 of 50
11. Question
A pharmacy technician finds an unlabeled syringe filled with an unknown liquid in the sterile compounding area. What should be done?
Correct
Unlabeled syringes pose serious safety risks. Proper disposal and documentation prevent accidental administration.
Incorrect
Unlabeled syringes pose serious safety risks. Proper disposal and documentation prevent accidental administration.
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Question 12 of 50
12. Question
A patient with kidney disease is prescribed ibuprofen. What should be done?
Correct
Ibuprofen can worsen kidney disease. The prescriber must confirm whether an alternative is needed.
Incorrect
Ibuprofen can worsen kidney disease. The prescriber must confirm whether an alternative is needed.
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Question 13 of 50
13. Question
Which error prevention strategy is most effective for reducing dispensing errors?
Correct
Barcode scanning and double verification are the most effective ways to reduce dispensing errors by ensuring accurate medication matching.
Incorrect
Barcode scanning and double verification are the most effective ways to reduce dispensing errors by ensuring accurate medication matching.
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Question 14 of 50
14. Question
What should a pharmacy technician do if they notice a dispensing error before the patient receives the medication?
Correct
Pharmacy technicians must immediately correct the error and inform the pharmacist to prevent harm before the patient receives the medication.
Incorrect
Pharmacy technicians must immediately correct the error and inform the pharmacist to prevent harm before the patient receives the medication.
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Question 15 of 50
15. Question
A technician notices a physician prescribed digoxin to a patient also taking spironolactone. What is the technician’s responsibility?
Correct
Spironolactone increases potassium, which can raise digoxin toxicity risk. Verification ensures patient safety.
Incorrect
Spironolactone increases potassium, which can raise digoxin toxicity risk. Verification ensures patient safety.
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Question 16 of 50
16. Question
Which strategy is most effective for preventing mix-ups between LASA medications?
Correct
A combination of Tall Man lettering and barcode scanning significantly reduces LASA medication errors by improving visibility and verification accuracy.
Incorrect
A combination of Tall Man lettering and barcode scanning significantly reduces LASA medication errors by improving visibility and verification accuracy.
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Question 17 of 50
17. Question
A patient reports experiencing a rapid heart rate after receiving an incorrect dose of levothyroxine. Upon checking, the pharmacy technician finds that the prescription was incorrectly filled with 200 mcg instead of 100 mcg. What should be done first?
Correct
Levothyroxine overdose can cause serious cardiovascular effects. The pharmacist must assess the severity and notify the prescriber for corrective action. Documentation ensures future prevention.
Incorrect
Levothyroxine overdose can cause serious cardiovascular effects. The pharmacist must assess the severity and notify the prescriber for corrective action. Documentation ensures future prevention.
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Question 18 of 50
18. Question
Which organization provides a list of look-alike/sound-alike (LASA) medications?
Correct
The Institute for Safe Medication Practices (ISMP) maintains a list of LASA medications to help healthcare professionals prevent medication errors caused by similar drug names.
Incorrect
The Institute for Safe Medication Practices (ISMP) maintains a list of LASA medications to help healthcare professionals prevent medication errors caused by similar drug names.
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Question 19 of 50
19. Question
A technician notices that an order for vancomycin IV states a dose much higher than usual. What is the best course of action?
Correct
Vancomycin dosing errors can cause nephrotoxicity and ototoxicity. Verification ensures patient safety.
Incorrect
Vancomycin dosing errors can cause nephrotoxicity and ototoxicity. Verification ensures patient safety.
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Question 20 of 50
20. Question
What is the primary reason for barcode scanning in medication dispensing?
Correct
Barcode scanning verifies medication accuracy by matching it to the prescription, reducing dispensing errors and improving patient safety.
Incorrect
Barcode scanning verifies medication accuracy by matching it to the prescription, reducing dispensing errors and improving patient safety.
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Question 21 of 50
21. Question
Which strategy is used to reduce confusion between look-alike/sound-alike (LASA) drugs?
Correct
Tall Man lettering highlights differences in LASA drug names to reduce errors (e.g., traZODone vs. traMADol). This strategy enhances readability and minimizes medication mix-ups.
Incorrect
Tall Man lettering highlights differences in LASA drug names to reduce errors (e.g., traZODone vs. traMADol). This strategy enhances readability and minimizes medication mix-ups.
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Question 22 of 50
22. Question
What should be done if a patient reports that their medication looks different from previous refills?
Correct
Any patient concerns about medication appearance should be verified to rule out dispensing errors and ensure patient safety.
Incorrect
Any patient concerns about medication appearance should be verified to rule out dispensing errors and ensure patient safety.
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Question 23 of 50
23. Question
A technician preparing a chemotherapy drug accidentally touches the vial’s rubber stopper with ungloved hands. What is the best course of action?
Correct
Chemotherapy drugs require strict aseptic handling. Any contamination can compromise sterility and patient safety, necessitating disposal.
Incorrect
Chemotherapy drugs require strict aseptic handling. Any contamination can compromise sterility and patient safety, necessitating disposal.
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Question 24 of 50
24. Question
What is the purpose of using auxiliary labels on medications?
Correct
Auxiliary labels provide safety instructions such as “Take with food” or “May cause drowsiness,” ensuring proper medication use and reducing errors.
Incorrect
Auxiliary labels provide safety instructions such as “Take with food” or “May cause drowsiness,” ensuring proper medication use and reducing errors.
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Question 25 of 50
25. Question
Why is it important to separate inventory of LASA medications?
Correct
Separating LASA medications prevents accidental mix-ups, significantly reducing medication dispensing errors.
Incorrect
Separating LASA medications prevents accidental mix-ups, significantly reducing medication dispensing errors.
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Question 26 of 50
26. Question
Which of the following is considered a prescribing error?
Correct
Prescribing errors occur when a physician prescribes a drug inappropriately, such as prescribing a medication to which the patient is allergic.
Incorrect
Prescribing errors occur when a physician prescribes a drug inappropriately, such as prescribing a medication to which the patient is allergic.
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Question 27 of 50
27. Question
A patient with a history of opioid use disorder is prescribed oxycodone for post-surgical pain. What is the technician’s best action?
Correct
Patients with opioid use disorder require careful medication management. The pharmacist must assess the appropriateness of oxycodone and consider alternatives if necessary.
Incorrect
Patients with opioid use disorder require careful medication management. The pharmacist must assess the appropriateness of oxycodone and consider alternatives if necessary.
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Question 28 of 50
28. Question
Which of the following is an example of a system-based medication error?
Correct
System-based errors involve factors like poor pharmacy layout or unclear labeling, leading to mistakes in medication dispensing.
Incorrect
System-based errors involve factors like poor pharmacy layout or unclear labeling, leading to mistakes in medication dispensing.
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Question 29 of 50
29. Question
A pharmacy technician observes that a bottle of metronidazole suspension is stored upright instead of being shaken before dispensing. What should be done before giving it to the patient?
Correct
Metronidazole suspension must be shaken properly to ensure uniform drug distribution. Dispensing without proper mixing can lead to incorrect dosing.
Incorrect
Metronidazole suspension must be shaken properly to ensure uniform drug distribution. Dispensing without proper mixing can lead to incorrect dosing.
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Question 30 of 50
30. Question
A patient picking up a new prescription for fentanyl patches asks if they can cut them in half for a lower dose. What should the pharmacy technician do?
Correct
Cutting fentanyl patches can lead to uncontrolled drug release, increasing overdose risk. The pharmacist must provide guidance.
Incorrect
Cutting fentanyl patches can lead to uncontrolled drug release, increasing overdose risk. The pharmacist must provide guidance.
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Question 31 of 50
31. Question
A technician observes that a patient’s prescription label reads “Take two tablets daily” for levothyroxine. The original prescription says “Take one tablet daily.” What should be done?
Correct
Levothyroxine dosing errors can cause serious thyroid imbalances. Verification ensures the correct dose is given.
Incorrect
Levothyroxine dosing errors can cause serious thyroid imbalances. Verification ensures the correct dose is given.
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Question 32 of 50
32. Question
A patient reports severe itching and rash after taking a new antibiotic. What should the pharmacy do?
Correct
Adverse drug reactions must be documented and reported to the prescriber to assess the severity and adjust therapy.
Incorrect
Adverse drug reactions must be documented and reported to the prescriber to assess the severity and adjust therapy.
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Question 33 of 50
33. Question
Why is hand hygiene critical in pharmacy settings?
Correct
Proper hand hygiene prevents contamination and maintains a sterile environment, reducing the risk of infections and ensuring medication integrity.
Incorrect
Proper hand hygiene prevents contamination and maintains a sterile environment, reducing the risk of infections and ensuring medication integrity.
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Question 34 of 50
34. Question
A technician finds expired fentanyl patches on pharmacy shelves. What should be done?
Correct
Expired controlled substances must be disposed of properly using DEA-approved methods to prevent diversion.
Incorrect
Expired controlled substances must be disposed of properly using DEA-approved methods to prevent diversion.
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Question 35 of 50
35. Question
A patient is prescribed insulin glargine but receives insulin lispro instead. What is the best action?
Correct
Insulin errors can lead to serious consequences. Reporting the error ensures the correct insulin is dispensed.
Incorrect
Insulin errors can lead to serious consequences. Reporting the error ensures the correct insulin is dispensed.
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Question 36 of 50
36. Question
What should be done if a pharmacist notices a prescription with an unusually high dose for a pediatric patient?
Correct
Unusual dosing for pediatric patients should always be verified with the prescriber before dispensing to prevent overdosing.
Incorrect
Unusual dosing for pediatric patients should always be verified with the prescriber before dispensing to prevent overdosing.
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Question 37 of 50
37. Question
A technician finds that a newly arrived shipment of insulin vials was left at room temperature for several hours. What is the most appropriate next step?
Correct
Insulin stability depends on proper storage conditions. The manufacturer should confirm whether the vials are still effective before dispensing.
Incorrect
Insulin stability depends on proper storage conditions. The manufacturer should confirm whether the vials are still effective before dispensing.
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Question 38 of 50
38. Question
What is the primary purpose of a medication reconciliation process?
Correct
Medication reconciliation ensures an accurate and complete medication history, preventing drug interactions and duplicate therapy errors.
Incorrect
Medication reconciliation ensures an accurate and complete medication history, preventing drug interactions and duplicate therapy errors.
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Question 39 of 50
39. Question
Which of the following drugs is considered high-alert due to its narrow therapeutic index?
Correct
Warfarin has a narrow therapeutic index, meaning small dosing variations can cause severe bleeding or clotting risks, making it a high-alert medication.
Incorrect
Warfarin has a narrow therapeutic index, meaning small dosing variations can cause severe bleeding or clotting risks, making it a high-alert medication.
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Question 40 of 50
40. Question
Which of the following is the best way to prevent cross-contamination when compounding medications?
Correct
Cleaning equipment with alcohol between uses prevents cross-contamination and ensures the purity of compounded medications.
Incorrect
Cleaning equipment with alcohol between uses prevents cross-contamination and ensures the purity of compounded medications.
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Question 41 of 50
41. Question
Which of the following is an example of a near-miss event in a pharmacy?
Correct
A near-miss occurs when an error is caught before reaching the patient, allowing corrective action before harm occurs.
Incorrect
A near-miss occurs when an error is caught before reaching the patient, allowing corrective action before harm occurs.
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Question 42 of 50
42. Question
A pharmacy technician is preparing to dispense metformin but notices that the prescription label reads “methimazole.” What should be done first?
Correct
Metformin and methimazole are LASA drugs with different uses. Verification with the prescriber ensures the correct medication is dispensed and prevents serious patient harm.
Incorrect
Metformin and methimazole are LASA drugs with different uses. Verification with the prescriber ensures the correct medication is dispensed and prevents serious patient harm.
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Question 43 of 50
43. Question
A technician observes a colleague skipping the barcode scanning step while dispensing high-alert medications. What should they do?
Correct
Skipping barcode scanning increases the risk of errors. Reporting to the pharmacist ensures compliance with safety protocols and patient safety.
Incorrect
Skipping barcode scanning increases the risk of errors. Reporting to the pharmacist ensures compliance with safety protocols and patient safety.
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Question 44 of 50
44. Question
Which process is used to verify a patient’s complete medication history and avoid drug interactions?
Correct
Medication reconciliation ensures a complete and accurate patient medication history to prevent drug interactions and duplication errors.
Incorrect
Medication reconciliation ensures a complete and accurate patient medication history to prevent drug interactions and duplication errors.
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Question 45 of 50
45. Question
What is the main goal of medication error reporting?
Correct
Medication error reporting helps identify risks, improve procedures, and prevent future errors, ensuring better patient safety without focusing on blame.
Incorrect
Medication error reporting helps identify risks, improve procedures, and prevent future errors, ensuring better patient safety without focusing on blame.
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Question 46 of 50
46. Question
A nurse calls the pharmacy stating that a patient received lorazepam instead of lansoprazole. What should the pharmacy do first?
Correct
An investigation into how the error occurred is necessary before reporting it as a medication error. The pharmacist must review the case to ensure corrective action.
Incorrect
An investigation into how the error occurred is necessary before reporting it as a medication error. The pharmacist must review the case to ensure corrective action.
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Question 47 of 50
47. Question
A patient with diabetes reports taking their extended-release metformin tablet whole but noticing the outer shell in their stool. What is the best response?
Correct
Extended-release tablets often have an outer shell that does not dissolve. Patients should be educated on medication absorption to prevent unnecessary concerns.
Incorrect
Extended-release tablets often have an outer shell that does not dissolve. Patients should be educated on medication absorption to prevent unnecessary concerns.
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Question 48 of 50
48. Question
Which of the following best describes a near-miss medication error?
Correct
A near-miss occurs when a medication error is identified and corrected before reaching the patient, preventing potential harm.
Incorrect
A near-miss occurs when a medication error is identified and corrected before reaching the patient, preventing potential harm.
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Question 49 of 50
49. Question
Which of the following situations requires immediate pharmacist intervention?
Correct
Doses that are inappropriate for a patient’s age require pharmacist intervention to prevent adverse effects and dosing errors.
Incorrect
Doses that are inappropriate for a patient’s age require pharmacist intervention to prevent adverse effects and dosing errors.
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Question 50 of 50
50. Question
Which of the following is considered a medication error?
Correct
Dispensing the wrong medication (e.g., amoxicillin instead of amlodipine) is a medication error that can lead to serious health risks and must be reported.
Incorrect
Dispensing the wrong medication (e.g., amoxicillin instead of amlodipine) is a medication error that can lead to serious health risks and must be reported.